You can do different things with each Echo product at the same time... for instance, play music in the living room, set and use a timer in the kitchen, and look up metric to SEA conversions in the garage all at the same time. They only need access to the wireless router to be able to function effectively. so if your garage is too far from the router, you may have issues, but not with the echo itself... it does what it can. if it loses connection due to distance or poor connection or whatever, it will light up and a blue ring will circle the top of the echo or the dots... I don't regularly us my echo devices for music, so I don't know whether you will have access to different music in each location but that subject is discussed regularly on these forums... probably best to seek advice on that item particularly... A good search may yield enough help with music stuff as well.